I had that happen to my total surprise... I have 45 pilots, had Thruxtons, did not do it then. I felt I was too rich so I went back to the stock needles with 1 shim.
The bike really lit up... guess I found the right balance. My theory is NOW the engine is really pulling for fuel, rather than me pushing fuel at it that it could not use.
I think I am simply running out of fuel when I hit the limiter and stay on it into 3rd gear.
What's a guy to do?