After the failed Soyus launch, they've determined that the abort was caused by a failed sensor. They worked out what to do to stop that happening. They've scheduled the next launch for Dec. 3.
Elsewhere in space, the Hubble telescope is scheduled to be decommissioned. As far as I know, the only real problem is a failed gyro. If they had enough sense to get a working replacement before closing down the shuttle program, they could probably go fix it again.
