Rich, this will sound painfully practical, but get thee to a physician. It may be grief, the stress of everything you've been dealing with and a bit of wanderlust, but rule out any medical issues first. Then step back and indulge yourself in some ME time. Sometimes, just a week's separation from the daily grind is enough to clear your mind and get things back in synch.
Don't be reluctant to ask for help with your mom. There are plenty of very good organizations to help. My mom lives 400+ miles away and when she started slipping about 3 years ago, we moved her and her cat into a senior living apartment (she's 96 now). Almost immediately, the burden of worry was gone, knowing that she had people around her and didn't have to drive or cook anymore. Being with friends all day, she's now healthier and more active than she was 5 years ago.
