Depending upon where you fly into for instance Vegas you could pick a central location like Flagstaff and find an Air BnB on line to rent. Then do shamrock touring from there Grand Canyon one day, Sedona Jerome Prescott and back around. East towards other destinations then back to the same Airbnb where you can be all set up. If you have enough time do that from a couple locations. Because many have a kitchen you can save $ on food for all your meals reserving it for some of the fine brew you might come across.