I was making the assumption that he was replacing the chain and wanted to align the back wheel not doing a complete wheel alignment.
So unless there is side to side movement when ya jack the bike up or some sign that there is bearing wear, a simple measure from the pivot to the axle center should suffice.
Sometimes the manufacturer will make an error in fabricating the wheel spacers. Its not common but has happened. And it has happened that the drive train is installed slightly a skew. Also not very common.
That's more of an older Harley issue, and that happens more than ya think.
If ya do pull the whole wheel then you should check the bearings and the wheel spacers.
Out side of them issues, right back to Factory is generally good.
