With these seats, I think three things come into play.
Buttockal width has been mentioned.
Handlebar distance has been mentioned.
Leg length - if your legs are shorter, they set straighter, or more parallel the ground, and this puts a little more weight on the back of your upper thigh / lower glute area. If your legs are longer, your legs will be bent more and more weight will sit on your tailbone. I'm 5'-7.5" with approx 30" inseam and the stock Speedmaster seat has been fine for a a couple of hours at a stretch.
Maybe when discussing seats, we need to include our height, weight, inseam, sleeve length and the width of our butts?
Nah.