I don't set out in the rain but I don't let moderate chances of rain make me stay off the bike either. I've been wet before and I'll be wet again. I figure that my skin is water tight and I'll get to change clothes when I get where I'm going. That said, try to avoid the painted arrows and crosswalk lines, they can be slippery, ditto steel strips on bridges and steel bridges themselves, give yourself more room to stop and accelerate more slowly, assume you are even MORE invisible, I stay on the highest/driest part of the road, and if you're going on a long trip pack some good rain gear.