Pat's calculator yields results that should serve as a starting point when you jet due to a throughput change. After installing the recommend jets, you may have to alter the recommended jets. Plug chops, seat of the pants and even a dyno run will fine tune the selections. Check for the best main first. Then the best midrange setup (jet needles/shims, etc) then the pilot circuit. Sure fuel makes a difference, but not to the point where using the first iteration of Pat's recommended jetting would be a concern. Operative words: Starting point.
