I had the ISOs. My only real beef with them was that:
1. they are much longer than OEMs. So, the brake and clutch only run 3/4 of the way down the grip. I had a couple of misgrabs, forcing me to get used to keeping my hands more 'in-board'.
2. Much Thicker. Fellas with smaller hands..like me.. need to get used to the new reach length for the brake and clutch.