If your bags are locked under your seat (the flap that goes across the fender) they are relitivaly safe. If someone wants your bags bad enough they will use a blade and cut them off,,then go to a leather shop and get them fixed or just steel whats in them.

Mal: "Y'all see the man hanging out of the spaceship with the really big gun?{ref, Jayne} Man's lookin' to kill some folk. So really, it's his will y'all should worry about thwarting."