The roads will be in crap condition. There will be road crews hiding around every turn working on that and, when they move to the next bend, they will leave behind fresh oil, gravel and sand.
Wildlife and loose pets will be out in abundance. So will the bicycle people, proving once again that those silly looking tight black pants cut off the circulation to your good sense.
Water running across the road will usually not cause any problems other than the buildup of a sand or gravel hump at the edges. You will be OK as long as you remember the slippery road rule, "never do anything suddenly". If your state salts roads in the winter, be sure to wash your bike thoroughly as soon as you get home, paying particular attention to the underside and inside the mudguards.
