Also read it many, many years ago and I am currently about half way through a re-read. I find it significant from several perspectives - 1. As XLD said, it relates to doing things correctly. 2. It deals with 'oneness' between man and machine - more precisely, between the human thought process and functionality of inanimate objects. 3. Relates and brings forth many great memories of motorcycling of yesterday - Many of which I'm pleased are just memory. 4. Relates to both the joy and struggle of the journey - both riding motorcycles and life itself.
I get lost in some of the mythology at many points at it sometimes requires a re-read or a wait-and-see to get the point - But then I'm just a poor country boy.
I suppose anyone with a philosophical sense can enjoy it and take something from it, but I suppose being a motorcycle nut makes it a lot less dry and places a bit more meaning to it all.