I used to run high beam all the time, I would dip it when flashed because I knew that they saw me, and I don't want someone driving two or three tons of iron at a high rate of speed in my general direction to be blinded. Now I just use it at night when I need the extra illumination. The rest of the time it's low beam.
The reason for my change? It's all about being seen, if they see me, maybe they won't do something stupid in front of me.
High beams can make it difficult for other road users to see your turn signals. That simple. I want them to know I'm changing lanes or turning. If I want to be sure that cage coming the other way in the left turn lane sees me, I flash the highs a couple of times. Far more likely to get their attention than a constant beam.